FAK — new target for antiangiogenic therapy
نویسندگان
چکیده
منابع مشابه
ALK1 as an emerging target for antiangiogenic therapy of cancer.
Members of the TGF-β family act on many, if not all, cell types within the body, producing diverse and complex cellular outcomes. Activation of the endothelial cell-restricted TGF-β type I receptor ALK1 results from the binding of several different ligands of the TGF-β family, including bone morphogenetic protein (BMP) 9, BMP10, and TGF-β. Mounting genetic, pharmacologic, and histopathologic ev...
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ژورنال
عنوان ژورنال: Nature Reviews Clinical Oncology
سال: 2016
ISSN: 1759-4774,1759-4782
DOI: 10.1038/nrclinonc.2016.69